Mostly routine maintenance till around 200k.... Suspension lower control arms/ shocks/ spark plugs etc... Almost exactly at 200k, radiator blew and exhaust manifold cracked. Both of which are a complete bitch to fix.
Engine and trans still running strong... both on synthetic.
There's a good handful of people in the 200k+ range. Most cars are perfectly happy getting to the 200k+ range so long as you care for them properly and don't thrash on them.
There was a thread on here somewhere about people and their V6 milage but I can't seem to find it.
My 04 V6 has ~270,000KM (about 168,000 miles) and it still runs beautifully. I still get great gas mileage and plenty of power still on tap. You should easily see 250,000 miles if you do maintenance and you don't treat it like a rental car.
Don't forget that an automatic transmission IS a wear item and not designed to last the life of the car, just like a clutch. If you manage to keep your auto transmission alive for 250,000 miles or more then you are caring for it well, but they do by nature consume themselves at a slow rate so having to rebuild it once should be considered maintenance, in my opinion at least.
327,000 miles on my 2004 6s before I lost compression in one cylinder. Manual transmission though with one clutch replacement. Had to replace the water pump, alternator, accordion intake hose, dogbone motor mount, 1 front axle and 1 front axle boot and both pre-cats but otherwise normal maintenance parts.
i hit 370,000 miles yesterday on my 2005 6s atx 5-door. bought it new so i've had it all this time. original engine and transmission. had to replace the control arms a couple months ago, it rides nice and tight now. last year i replaced the starter and valve cover gaskets and intake manifold gaskets. other than the replacing the intake hose and maf sensor a few years ago, i've only spent $$ on normal maintenance stuff. leaks a little bit of oil...a quart every 1000-2000 miles so it's not that bad, but it drips onto the exhaust manifold...i'm pretty much over the smell of burning oil, but i'm not gonna spend the $$ to fix the leak